Calantha is first mentioned by Iggy as he recounts his experience there to fellow replicant Trixie. Iggy begins his story with "I saw the truth on the fields of Calantha". We are shown his experience in combat, where following a violent engagement, he comes across the corpse of an enemy combatant. Iggy then proceeds to check the dead soldiers right eye. Upon realizing that the dead soldier was also Nexus, Iggy says "That's when I realized both sides were Nexus. Nothing more than toy soldiers in a sandbox".
Calantha is also referenced in Blade Runner 2049 by LAPD Officer K, as he questions Sapper Morton inside his home. Upon noticing Sapper's utility bag, K mentions that such bags are military issue only, given to combat model Nexus in warzones such as Calantha. K adds that Calantha "Must have been brutal".